PCBP1 anticorps (AA 152-268)

N° du produit ABIN7870977

L’anticorps anti-PCBP1 Polyclonal Lapin est utilisé pour la détection de PCBP1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC (p) et FACS.

Aperçu rapide pour PCBP1 anticorps (AA 152-268) (ABIN7870977)

Antigène: PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCBP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-PCBP1 anticorps

Épitope: AA 152-268

Fonction: PCBP1 Antibody

Purification: Affinity purified

Immunogène: A human recombinant partial protein (amino acids P152-K268) was used as the immunogen for the PCBP1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PCBP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PCBP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PCBP1

Antigène: PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

Autre désignation: PCBP1

Sujet: Poly(rC)-binding protein 1 is a protein that in humans is encoded by the PCBP1 gene. This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.

UniProt: Q15365