Cathepsin K anticorps (AA 163-274)

N° du produit ABIN7871121

L’anticorps anti-Cathepsin K Monoclonal Souris est utilisé pour la détection de Cathepsin K dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Cathepsin K anticorps (AA 163-274) (ABIN7871121)

Antigène: Cathepsin K (CTSK)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cathepsin K est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: CTSK-2793

Détail du produit anti-Cathepsin K anticorps

Épitope: AA 163-274

Fonction: Cathepsin K Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 163-274) was used as the immunogen for the Cathepsin K antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Cathepsin K antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Cathepsin K antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Cathepsin K

Antigène: Cathepsin K (CTSK)

Autre désignation: Cathepsin K

Sujet: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

UniProt: P43235

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades