IRF4 anticorps (AA 163-419)

N° du produit ABIN7871126

Cet anticorps Lapin Polyclonal détecte spécifiquement IRF4 dans WB, ELISA et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour IRF4 anticorps (AA 163-419) (ABIN7871126)

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-IRF4 anticorps

Épitope: AA 163-419

Fonction: Interferon regulatory factor 4 Antibody / IRF4 / MUM1

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived human recombinant protein (amino acids A163-Q419) was used as the immunogen for the Interferon regulatory factor 4 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Interferon regulatory factor 4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Interferon regulatory factor 4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur IRF4

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Autre désignation: Interferon regulatory factor 4

Sujet: Interferon regulatory factor 4 (IRF4), also known as Multiple myeloma oncogene 1 (MUM1), is a protein that in humans is encoded by the IRF4 gene. It is located on 6p25.3. IRF4 is a transcription factor, and it is essential for the development of T helper-2 (Th2) cells, IL17 -producing Th17 cells, and IL9 -producing Th9 cells. In melanocytic cells, the IRF4 gene may be regulated by MITF. IRF4 is a transcription factor that has been implicated in acute leukemia. This gene is strongly associated with pigmentation, sensitivity of skin to sun exposure, freckles, blue eyes, and brown hair color. What's more, IRF4 inhibition is toxic to myeloma cell lines, regardless of transforming oncogenic mechanism.

UniProt: Q15306

Pathways: Chromatin Binding