CDC45 anticorps (AA 166-431)

N° du produit ABIN7871157

L’anticorps anti-CDC45 Monoclonal Souris est utilisé pour la détection de CDC45 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, FACS et IHC (p).

Aperçu rapide pour CDC45 anticorps (AA 166-431) (ABIN7871157)

Antigène: CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDC45 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6H6

Détail du produit anti-CDC45 anticorps

Épitope: AA 166-431

Fonction: PORC-PI-1 Antibody / CDC45

Purification: Affinity purified

Immunogène: A human recombinant partial protein (amino acids E166-A431) was used as the immunogen for the PORC-PI-1 antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the PORC-PI-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PORC-PI-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CDC45

Antigène: CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))

Autre désignation: PORC-PI-1

Sujet: CDC45 is a protein that in humans is encoded by the CDC45 gene. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.

UniProt: O75419

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA