ZNF488 anticorps (AA 170-307)

N° du produit ABIN7871250

L’anticorps anti-ZNF488 Monoclonal Souris est utilisé pour la détection de ZNF488 dans des échantillons de Humain. Il a été validé pour FACS et IHC (p).

Aperçu rapide pour ZNF488 anticorps (AA 170-307) (ABIN7871250)

Antigène: ZNF488 (Zinc Finger Protein 488 (ZNF488))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ZNF488 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PCRP-ZNF488-2D8

Détail du produit anti-ZNF488 anticorps

Épitope: AA 170-307

Fonction: ZNF488 Antibody

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein (within amino acids 170-307) from the human protein was used as the immunogen for the ZNF488 antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the ZNF488 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ZNF488 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur ZNF488

Antigène: ZNF488 (Zinc Finger Protein 488 (ZNF488))

Autre désignation: ZNF488

Sujet: Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF488 is a 340 amino acid transcriptional regulator belonging to the Kruppel C2H2-type zinc finger protein family. ZNF488 localizes to the nucleus and contains two C2H2-type zinc fingers. ZNF488 is encoded by a gene located on chromosome 10, which contains a plethora of interesting genes and represents between 4 and 4.5 percent of the total DNA in cells. Jackson-Weiss, Cowden and Usher syndromes are a few diseases related to genes on chromosome 10.

UniProt: Q96MN9