LSP1 anticorps (AA 174-278)

N° du produit ABIN7871287

Cet anticorps anti-LSP1 Monoclonal Souris (Clone LSP1-3042) (ABIN7871287) détecte spécifiquement LSP1 dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour LSP1 anticorps (AA 174-278) (ABIN7871287)

Antigène: LSP1 (Lymphocyte-Specific Protein 1 (LSP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LSP1 est non-conjugé

Application: ELISA

Clone: LSP1-3042

Détail du produit anti-LSP1 anticorps

Épitope: AA 174-278

Fonction: LSP1 Antibody / Lymphocyte Specific Protein 1

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 174-278) was used as the immunogen for this LSP1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the LSP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the LSP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur LSP1

Antigène: LSP1 (Lymphocyte-Specific Protein 1 (LSP1))

Autre désignation: LSP1

Sujet: LSP1 is a hematopoietic-expressed gene that encodes an F-actin-binding, leukocyte-specific (including B and T lymphocytes, granulocytes and macrophages), phosphoprotein. However, mRNA splice variants that do not encode the lympho-specific protein are expressed from this gene in nonlymphoid cell lines as well (myocytes, stromal cells and fibroblasts), suggesting pp52 has a divergent role in signal transduction. The pp52 (LSP1) locus maps to human chromosome 11p15.5, which is implicated in tumor-related chromosomal translocations found in chronic lymphocytic leukemia. The pp52 promoter contains key elements that control transcriptional activity including an initiator specifying the unique 5' terminus of pp52 mRNA, tandem pairs of Ets and SP1 motifs, and a single C/EBP motif. LSP1 binds the cytoskeleton and has been implicated in affecting cytoskeletal remodeling in a variety of leukocyte functions, including cell motility and chemotaxis.

UniProt: P33241