Villin 1 anticorps (AA 179-311)

N° du produit ABIN7871352

L’anticorps anti-Villin 1 Monoclonal Souris est utilisé pour la détection de Villin 1 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Villin 1 anticorps (AA 179-311) (ABIN7871352)

Antigène: Villin 1 (VIL1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Villin 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: VIL1-2376

Détail du produit anti-Villin 1 anticorps

Épitope: AA 179-311

Fonction: Villin Antibody

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 179-311) was used as the immunogen for this Villin antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Villin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Villin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Villin 1

Antigène: Villin 1 (VIL1)

Autre désignation: Villin

Sujet: Recognizes a protein of 95 kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.

UniProt: P09327

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization