Recombinant Villin 1 anticorps (AA 179-311)

N° du produit ABIN7871355

L’anticorps anti-Villin 1 Monoclonal Lapin est utilisé pour la détection de Villin 1 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant Villin 1 anticorps (AA 179-311) (ABIN7871355)

Antigène: Villin 1 (VIL1)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Villin 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: VIL1-2310R

Détail du produit anti-Villin 1 anticorps

Épitope: AA 179-311

Fonction: Recombinant Villin Antibody / VIL1 (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogène: Amino acids 179-311 from the human protein were used as the immunogen for this recombinant Villin antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the recombinant Villin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant Villin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Villin 1

Antigène: Villin 1 (VIL1)

Autre désignation: Villin

Sujet: Recognizes a protein of 95 kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.

UniProt: P09327

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization