SELPLG anticorps (AA 18-420)

N° du produit ABIN7871418

L’anticorps anti-SELPLG Polyclonal Lapin est utilisé pour la détection de SELPLG dans des échantillons de Souris et Rat. Il a été validé pour FACS, WB, ELISA et IHC (p).

Aperçu rapide pour SELPLG anticorps (AA 18-420) (ABIN7871418)

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SELPLG est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SELPLG anticorps

Épitope: AA 18-420

Fonction: Psgl-1 Antibody / Selplg

Purification: Affinity purified

Immunogène: Recombinant rat protein (amino acids L18-P420) was used as the immunogen for the Psgl-1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Psgl-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Psgl-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SELPLG

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Autre désignation: Psgl-1

Sujet: Selectin P ligand, also known as SELPLG or CD162 (cluster of differentiation 162), is a human gene. It is mapped to 12q16. This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

UniProt: Q8K5B0