Prosaposin anticorps (AA 182-479)

N° du produit ABIN7871467

Cet anticorps anti-Prosaposin Polyclonal Lapin (ABIN7871467) détecte spécifiquement Prosaposin dans WB, ELISA, IF, IHC (p) et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Prosaposin anticorps (AA 182-479) (ABIN7871467)

Antigène: Prosaposin (PSAP)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prosaposin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-Prosaposin anticorps

Épitope: AA 182-479

Fonction: Prosaposin Antibody / PSAP

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids Q182-I479) was used as the immunogen for the Prosaposin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Prosaposin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Prosaposin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Prosaposin

Antigène: Prosaposin (PSAP)

Autre désignation: Prosaposin

Sujet: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

UniProt: P07602

Pathways: Positive Regulation of Endopeptidase Activity