CD226 anticorps (AA 19-254)

N° du produit ABIN7871578

Cet anticorps anti-CD226 Polyclonal Lapin (ABIN7871578) détecte spécifiquement CD226 dans WB, FACS et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CD226 anticorps (AA 19-254) (ABIN7871578)

Antigène: CD226

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD226 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Détail du produit anti-CD226 anticorps

Épitope: AA 19-254

Fonction: DNAM-1 Antibody / CD226

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids E19-A254) was used as the immunogen for the DNAM-1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the DNAM-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the DNAM-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CD226

Antigène: CD226

Autre désignation: DNAM-1

Sujet: DNAM 1, also known as CD226, is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints