Thrombospondin 1 anticorps (AA 19-268)

N° du produit ABIN7871580

L’anticorps anti-Thrombospondin 1 Polyclonal Lapin est utilisé pour la détection de Thrombospondin 1 dans des échantillons de Humain. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour Thrombospondin 1 anticorps (AA 19-268) (ABIN7871580)

Antigène: Thrombospondin 1 (THBS1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thrombospondin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-Thrombospondin 1 anticorps

Épitope: AA 19-268

Fonction: THBS1 Antibody / Thrombospondin

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids N19-A268) was used as the immunogen for the THBS1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the THBS1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the THBS1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Thrombospondin 1

Antigène: Thrombospondin 1 (THBS1)

Autre désignation: THBS1

Sujet: THBS1 is also known as Thrombospondin 1, TSP1. The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. It is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Also this protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. In addition, the thrombospondin-1 protein is a member of the thrombospondinfamily. It is a multi-domain matrix glycoprotein that has been shown to be a natural inhibitor of neovascularization and tumorigenesis in healthy tissue. Both positive and negative modulation of endothelial cell adhesion, motility, and growth have been attributed to TSP1. This should not be surprising considering that TSP1 interacts with at least 12 cell adhesion receptors, including CD36, ?v integrins, ?1 integrins, syndecan, and integrin-associated protein (IAP or CD47). It also interacts with numerous proteases involved in angiogenesis, including plasminogen, urokinase, matrix metalloproteinase, thrombin, cathepsin, and elastase.

UniProt: P07996

Pathways: Autophagy