Periostin anticorps (AA 193-326)

N° du produit ABIN7871683

Cet anticorps anti-Periostin Monoclonal Souris (Clone POSTN-4095) (ABIN7871683) détecte spécifiquement Periostin dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Periostin anticorps (AA 193-326) (ABIN7871683)

Antigène: Periostin (POSTN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Periostin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: POSTN-4095

Détail du produit anti-Periostin anticorps

Épitope: AA 193-326

Fonction: Periostin Antibody / POSTN (azide and preservative free)

Purification: Protein G affinity

Immunogène: A portion of amino acids 193-326 from human POSTN protein was used as the immunogen for the Periostin antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Periostin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the Periostin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Periostin

Antigène: Periostin (POSTN)

Autre désignation: Periostin

Sujet: Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for AlphaVbeta3 and AlphaVbeta5 integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor beta 1 (TGF beta 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.

UniProt: Q15063