Recombinant CNN1 anticorps (AA 197-297)

N° du produit ABIN7871743

Cet anticorps anti-CNN1 Monoclonal Souris (Clone rCNN1-6918) (ABIN7871743) détecte spécifiquement CNN1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant CNN1 anticorps (AA 197-297) (ABIN7871743)

Antigène: CNN1 (Calponin 1 (CNN1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CNN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: RCNN1-6918

Détail du produit anti-CNN1 anticorps

Épitope: AA 197-297

Fonction: CNN1 Antibody / Calponin 1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 197-297) from the human protein was used as the immunogen for the CNN1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the CNN1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the CNN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CNN1

Antigène: CNN1 (Calponin 1 (CNN1))

Autre désignation: CNN1

Sujet: Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this mAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.

UniProt: P51911