Recombinant Filaggrin anticorps (AA 198-288)

N° du produit ABIN7871751

L’anticorps anti-Filaggrin Monoclonal Souris est utilisé pour la détection de Filaggrin dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant Filaggrin anticorps (AA 198-288) (ABIN7871751)

Antigène: Filaggrin (FLG)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Filaggrin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RFLG-1945

Détail du produit anti-Filaggrin anticorps

Épitope: AA 198-288

Fonction: Recombinant FLG Antibody / Filaggrin

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 198-288 was used as the immunogen for the recombinant FLG antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant FLG antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant FLG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Filaggrin

Antigène: Filaggrin (FLG)

Autre désignation: FLG

Sujet: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules.Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.

UniProt: P20930

Pathways: Sensory Perception of Sound, Stem Cell Maintenance