MED12 anticorps (AA 1991-2025)

N° du produit ABIN7871758

Cet anticorps anti-MED12 Polyclonal Lapin (ABIN7871758) détecte spécifiquement MED12 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour MED12 anticorps (AA 1991-2025) (ABIN7871758)

Antigène: MED12 (Mediator Complex Subunit 12 (MED12))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MED12 anticorps

Épitope: AA 1991-2025

Fonction: Med12 Antibody

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 1991-2025 from the mouse protein was used as the immunogen for the Med12 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Med12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Med12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MED12

Antigène: MED12 (Mediator Complex Subunit 12 (MED12))

Autre désignation: Med12

Sujet: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway (By similarity).

UniProt: A2AGH6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation