Cet anticorps Lapin Polyclonal détecte spécifiquement Histone H2A dans WB, ELISA, IHC (p), FACS et IP. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.
Optimal dilution of the Histone H2AX antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
-20 °C
Stockage commentaire
Store the Histone H2AX antibody at -20oC.
Antigène
Histone H2A
Sujet
H2A histone family member X (usually abbreviated as H2AX) is a type of histone protein from theH2A family encoded by the H2AFX gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.