L1CAM anticorps (AA 20-242)

N° du produit ABIN7871846

Cet anticorps Lapin Polyclonal détecte spécifiquement L1CAM dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour L1CAM anticorps (AA 20-242) (ABIN7871846)

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp L1CAM est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-L1CAM anticorps

Épitope: AA 20-242

Fonction: NCAM-L1 Antibody / L1CAM / CD171

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids I20-L242) was used as the immunogen for the NCAM-L1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the NCAM-L1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the NCAM-L1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur L1CAM

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Autre désignation: NCAM-L1

Sujet: L1, also known as L1CAM, is a transmembrane protein member of the L1 protein family, encoded by the L1CAM gene. The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.

UniProt: P32004

Pathways: Synaptic Membrane