PON1 anticorps (AA 20-252)

N° du produit ABIN7871850

L’anticorps anti-PON1 Polyclonal Lapin est utilisé pour la détection de PON1 dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour WB, ELISA et IHC (p).

Aperçu rapide pour PON1 anticorps (AA 20-252) (ABIN7871850)

Antigène: PON1 (Paraoxonase 1 (PON1))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PON1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PON1 anticorps

Épitope: AA 20-252

Fonction: Paraoxonase 1 Antibody / PON1

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids H20-A252) was used as the immunogen for the Paraoxonase 1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Paraoxonase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Paraoxonase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PON1

Antigène: PON1 (Paraoxonase 1 (PON1))

Autre désignation: Paraoxonase 1

Sujet: Serum paraoxonase/arylesterase 1 (PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-?, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.

UniProt: P27169