LRRC59 anticorps (AA 20-307)

N° du produit ABIN7871860

Cet anticorps anti-LRRC59 Polyclonal Lapin (ABIN7871860) détecte spécifiquement LRRC59 dans WB, IHC (p), ELISA, IF et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LRRC59 anticorps (AA 20-307) (ABIN7871860)

Antigène: LRRC59 (Leucine Rich Repeat Containing 59 (LRRC59))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC59 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-LRRC59 anticorps

Épitope: AA 20-307

Fonction: LRRC59 Antibody / Leucine-rich repeat-containing protein 59

Purification: Antigen affinity purified

Immunogène: An E.coli-derived human recombinant protein (amino acids L20-Q307) was used as the immunogen for the LRRC59 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the LRRC59 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the LRRC59 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur LRRC59

Antigène: LRRC59 (Leucine Rich Repeat Containing 59 (LRRC59))

Autre désignation: LRRC59

Sujet: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

UniProt: Q96AG4