Recombinant Splicing Factor 1 anticorps (AA 200-400)

N° du produit ABIN7872052

Cet anticorps anti-Splicing Factor 1 Monoclonal Lapin (Clone SF1-8150R) (ABIN7872052) détecte spécifiquement Splicing Factor 1 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant Splicing Factor 1 anticorps (AA 200-400) (ABIN7872052)

Antigène: Splicing Factor 1 (SF1)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Splicing Factor 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: SF1-8150R

Détail du produit anti-Splicing Factor 1 anticorps

Épitope: AA 200-400

Fonction: SF-1 Antibody / Steroidogenic Factor 1 / NR5A1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the SF-1 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the SF-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the SF-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Splicing Factor 1

Antigène: Splicing Factor 1 (SF1)

Autre désignation: SF-1

Sujet: Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development.SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.

UniProt: Q13285

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Maintenance of Protein Location