Recombinant Tyrosinase-Related Protein 1 anticorps (AA 200-400)

N° du produit ABIN7872065

Cet anticorps Lapin Monoclonal détecte spécifiquement Tyrosinase-Related Protein 1 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant Tyrosinase-Related Protein 1 anticorps (AA 200-400) (ABIN7872065)

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Tyrosinase-Related Protein 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TYRP1-8313R

Détail du produit anti-Tyrosinase-Related Protein 1 anticorps

Épitope: AA 200-400

Fonction: Tyrosinase-Related Protein-1 Antibody / TYRP1

Purification: Protein A affinity

Immunogène: A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the Tyrosinase-Related Protein-1 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the Tyrosinase-Related Protein-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Tyrosinase-Related Protein-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Tyrosinase-Related Protein 1

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Autre désignation: Tyrosinase-Related Protein-1

Sujet: It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

UniProt: P17643