SMPD1 anticorps (AA 204-558)

N° du produit ABIN7872093

L’anticorps anti-SMPD1 Polyclonal Lapin est utilisé pour la détection de SMPD1 dans des échantillons de Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour SMPD1 anticorps (AA 204-558) (ABIN7872093)

Antigène: SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMPD1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SMPD1 anticorps

Épitope: AA 204-558

Fonction: aSMase Antibody / Smpd1 / Acid sphingomyelinase

Purification: Antigen affinity purified

Immunogène: Recombinant mouse protein (amino acids D204-M558) was used as the immunogen for the aSMase antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the aSMase antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the aSMase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SMPD1

Antigène: SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))

Autre désignation: aSMase

Sujet: Sphingomyelin phosphodiesterase 1 (SMPD1), also known as acid sphingomyelinase (ASM or aSMase), is an enzyme that in humans is encoded by the SMPD1 gene. Enables acid sphingomyelin phosphodiesterase activity and zinc ion binding activity. Involved in ceramide biosynthetic process, positive regulation of apoptotic process, and response to ionizing radiation. Acts upstream of or within ceramide metabolic process, cholesterol metabolic process, and sphingomyelin catabolic process. Located in extracellular space. Is expressed in several structures, including alimentary system, integumental system, nervous system, sensory organ, and skeleton. Used to study Niemann-Pick disease. Human ortholog(s) of this gene implicated in Niemann-Pick disease, Niemann-Pick disease type A, and Niemann-Pick disease type B. Orthologous to human SMPD1 (sphingomyelin phosphodiesterase 1).

UniProt: Q04519