Apolipoprotein D anticorps (AA 21-119)

N° du produit ABIN7872129

L’anticorps anti-Apolipoprotein D Monoclonal Souris est utilisé pour la détection de Apolipoprotein D dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Apolipoprotein D anticorps (AA 21-119) (ABIN7872129)

Antigène: Apolipoprotein D (APOD)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Apolipoprotein D est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: APOD-3412

Détail du produit anti-Apolipoprotein D anticorps

Épitope: AA 21-119

Fonction: Apolipoprotein D Antibody / APOD

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 21-119 from the human protein was used as the immunogen for the Apolipoprotein D antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Apolipoprotein D antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Apolipoprotein D antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Apolipoprotein D

Antigène: Apolipoprotein D (APOD)

Autre désignation: Apolipoprotein D

Sujet: Lipids, such as phospholipids, triacylglycerols and cholesterol, are weakly soluble in aqueous solution and therefore are transported by circulation as components of lipoproteins. Lipoproteins are globular particles that consist of a non-polar core of triacylglycerols and cholesteryl esters surrounded by phospholipid, cholesterol and an amphiphilic coating of protein, known as apolipoproteins (apo). These complexes allow the dissolution and shuttling of their non-polar lipid components. At least nine different apolipoproteins are distributed in significant amounts in different human lipoproteins. Apolipoprotein D (apoD) is a member of the lipocalin superfamily of transporter proteins that bind small hydrophobic molecules, including arachidonic acid (AA). The ability of apoD to bind AA implicates it in pathways associated with membrane phospholipid signal transduction and metabolism. apoD expression has been shown to correlate both with cell cycle arrest and with prognosis in several types of malignancy, including central nervous system astrocytomas and medulloblastomas.

UniProt: P05090

Pathways: Platelet-derived growth Factor Receptor Signaling