NOX5 anticorps (AA 21-765)
Aperçu rapide pour NOX5 anticorps (AA 21-765) (ABIN7872181)
Antigène
Voir toutes NOX5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 21-765
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Fonction
- NOX5 Antibody
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Purification
- Affinity purified
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Immunogène
- Recombinant human protein (amino acids A21-F765) was used as the immunogen for the NOX5 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the NOX5 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the NOX5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NOX5 (NADPH Oxidase 5 (NOX5))
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Autre désignation
- NOX5
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Sujet
- NOX5 (Nadph Oxidase 5), also known as NOX5A or NOX5B, is a protein which in humans is encoded by the NOX5 gene. The International Radiation Hybrid Mapping Consortium mapped the NOX5 gene to chromosome 15. NOX5 is a novel NADPH oxidase that generates superoxide and functions as an H+ channel in a Ca2+-dependent manner. It is found that, when heterologously expressed, NOX5 was quiescent in unstimulated cells. However, in response to elevations of the cytosolic Ca2+ concentration, it generated large amounts of superoxide. Using RT-PCR and Southern and Western blot analyses, NOX5 was identified as a flavin-containing Ca2+-dependent oxidase present in hairy leukemic cells (HC), but not normal B cells.
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UniProt
- Q96PH1
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Pathways
- Proton Transport
Antigène
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