FERMT1 anticorps (AA 216-677)

N° du produit ABIN7872244

Cet anticorps anti-FERMT1 Monoclonal Souris (Clone 4A5-14) (ABIN7872244) détecte spécifiquement FERMT1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FERMT1 anticorps (AA 216-677) (ABIN7872244)

Antigène: FERMT1 (Fermitin Family Member 1 (FERMT1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FERMT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4A5-14

Détail du produit anti-FERMT1 anticorps

Épitope: AA 216-677

Fonction: Kindlin-1 Antibody / KIND1

Purification: Protein G affinity chromatography

Immunogène: Amino acids 216-677 from the human protein were used as the immunogen for the Kindlin-1 antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the Kindlin-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Kindlin-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur FERMT1

Antigène: FERMT1 (Fermitin Family Member 1 (FERMT1))

Autre désignation: Kindlin-1

Sujet: Kindlin-1 (also known as KIND1, KINDLERIN, UNC112-RELATED PROTEIN 1 (URP1) is an important component of cell-extracellular matrix adhesion. Kindlin-1 is involved in cell adhesion, possibly via its interaction with integrins and may mediate TGF-beta 1 signaling during tumor progression. Kindlin-1 has been shown to be significantly upregulated in lung and colon carcinomas. Mutations in the kindlin-1 gene, FERMT1, causes Kindler syndrome. Kindler syndrome is an autosomal recessive disorder characterized by neonatal blistering, sun sensitivity, atrophy, abnormal pigmentation and fragility of the skin. We have developed monoclonal anti-kidlin-1 antibodies. This monoclonal antibody recognizes kindlin-1 in multiple assays including Western blotting, immunoprecipitation, immunohistochemical and immunofluorescent staining.

UniProt: Q9BQL6