Cet anticorps anti-LIMS1 Polyclonal Lapin (ABIN7872286) détecte spécifiquement LIMS1 dans WB et IHC (p).
L’anticorps est réactif avec des échantillons de Poisson zèbre (Danio rerio).
LIMS1
Reactivité: Humain
IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 680
Indications d'application
Optimal dilution of the Zebrafish Lims1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
4 °C,-20 °C
Stockage commentaire
After reconstitution, the Zebrafish Lims1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Antigène
LIMS1
(LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
Autre désignation
Lims1
Sujet
LIM and senescent cell antigen-like-containing domain protein 1 is a protein that in humans is encoded by the LIMS1 gene. The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.