CTSC anticorps (AA 22-463)

N° du produit ABIN7872325

Cet anticorps anti-CTSC Polyclonal Lapin (ABIN7872325) détecte spécifiquement CTSC dans WB, ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CTSC anticorps (AA 22-463) (ABIN7872325)

Antigène: CTSC (Cathepsin C (CTSC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTSC est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-CTSC anticorps

Épitope: AA 22-463

Fonction: CTSC Antibody / Cathepsin C

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids V22-L463) was used as the immunogen for the CTSC antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CTSC antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the CTSC antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CTSC

Antigène: CTSC (Cathepsin C (CTSC))

Autre désignation: CTSC

Sujet: Cathepsin C (CTSC) also known as dipeptidyl peptidase I (DPP-I) is a lysosomal exo-cysteine protease belonging to the peptidase C1 protein family, a subgroup of the cysteine cathepsins. In humans, it is encoded by the CTSC gene. This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

UniProt: P53634