Ki-67 anticorps (AA 2293-2478)

N° du produit ABIN7872446

Cet anticorps Souris Monoclonal détecte spécifiquement Ki-67 dans WB, FACS, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Ki-67 anticorps (AA 2293-2478) (ABIN7872446)

Antigène: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ki-67 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: MKI67-6582

Détail du produit anti-Ki-67 anticorps

Épitope: AA 2293-2478

Fonction: Ki-67 Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant human Ki67 protein fragment (within amino acids 2293-2478) was used as the immunogen for the Ki-67 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Ki-67 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the Ki-67 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Ki-67

Antigène: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Autre désignation: Ki-67

Sujet: Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.

UniProt: P46013

Pathways: Glycosaminoglycan Metabolic Process