Ki-67 anticorps (AA 2293-2478)

N° du produit ABIN7872448

Cet anticorps anti-Ki-67 Monoclonal Souris (Clone PMKI67-1) (ABIN7872448) détecte spécifiquement Ki-67 dans FACS, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Ki-67 anticorps (AA 2293-2478) (ABIN7872448)

Antigène: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ki-67 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: PMKI67-1

Détail du produit anti-Ki-67 anticorps

Épitope: AA 2293-2478

Fonction: Ki67 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 2293-2478 was used as the immunogen for the Ki67 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Ki67 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Ki67 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Ki-67

Antigène: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Autre désignation: Ki67

Sujet: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. [UniProt]

UniProt: P46013

Pathways: Glycosaminoglycan Metabolic Process