Ki-67 anticorps (AA 2293-2478) (Biotin)

N° du produit ABIN7872451

Cet anticorps anti-Ki-67 Monoclonal Souris conjugué à Biotin (Clone MKI67-2465) (ABIN7872451) détecte spécifiquement Ki-67 dans FACS, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Ki-67 anticorps (AA 2293-2478) (Biotin) (ABIN7872451)

Antigène: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ki-67 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MKI67-2465

Détail du produit anti-Ki-67 anticorps (Biotin)

Épitope: AA 2293-2478

Fonction: Ki-67 Antibody

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 2293-2478 from the human protein was used as the immunogen for the Ki-67 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Ki-67 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Ki-67 antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).

Détails sur Ki-67

Antigène: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Autre désignation: Ki-67

Sujet: Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.

UniProt: P46013

Pathways: Glycosaminoglycan Metabolic Process