KLHL12 anticorps (AA 23-327)
Aperçu rapide pour KLHL12 anticorps (AA 23-327) (ABIN7872525)
Antigène
Voir toutes KLHL12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 23-327
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Fonction
- Zebrafish Klhl12 Antibody / Kelch-like protein 12
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Purification
- Antigen affinity chromatography
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Immunogène
- An E.coli-derived zebrafish Klhl12 recombinant protein (amino acids R23-V327) was used as the immunogen for the Zebrafish Klhl12 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Optimal dilution of the Zebrafish Klhl12 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Zebrafish Klhl12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
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Autre désignation
- Klhl12
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Sujet
- Kelch-like protein 12 is a protein that in humans is encoded by the KLHL12 gene. This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants.
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UniProt
- Q5U374
Antigène
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