ILF2 anticorps (AA 23-356)

N° du produit ABIN7872527

Cet anticorps Lapin Polyclonal détecte spécifiquement ILF2 dans WB, IF et IHC (p). Il présente une réactivité avec des échantillons de Poisson zèbre (Danio rerio).

Aperçu rapide pour ILF2 anticorps (AA 23-356) (ABIN7872527)

Antigène: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ILF2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ILF2 anticorps

Épitope: AA 23-356

Fonction: Zebrafish ILF2 Antibody / Interleukin enhancer-binding factor 2 / NF45

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived zebrafish NF45/ILF2 recombinant protein (amino acids Y23-K356) was used as the immunogen for the Zebrafish ILF2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish ILF2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish ILF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ILF2

Antigène: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Autre désignation: ILF2

Sujet: Interleukin enhancer-binding factor 2, also called 'Nuclear factor of activated T-cells 45 kDa,' is a protein that in humans is encoded by the ILF2 gene. The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.

UniProt: Q6NZ06