PLOD1 anticorps (AA 23-640)
Aperçu rapide pour PLOD1 anticorps (AA 23-640) (ABIN7872549)
Antigène
Voir toutes PLOD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 23-640
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Fonction
- PLOD1 Antibody / Lysyl hydroxylase 1 / LH1
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Purification
- Antigen affinity purified
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Immunogène
- An E.coli-derived human recombinant protein (amino acids K23-A640) was used as the immunogen for the PLOD1 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the PLOD1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the PLOD1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))
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Autre désignation
- PLOD1
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Sujet
- Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q02809
Antigène
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