SPTAN1 anticorps (AA 2351-2475)

N° du produit ABIN7872626

Cet anticorps Souris Monoclonal détecte spécifiquement SPTAN1 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SPTAN1 anticorps (AA 2351-2475) (ABIN7872626)

Antigène: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SPTAN1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPTAN1-3351

Détail du produit anti-SPTAN1 anticorps

Épitope: AA 2351-2475

Fonction: SPTAN1 Antibody / Alpha II Spectrin / Alpha Fodrin / NEAS

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 2351-2475) was used as the immunogen for this SPTAN1 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the SPTAN1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the SPTAN1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur SPTAN1

Antigène: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Autre désignation: SPTAN1

Sujet: Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous and chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Spectrin I and spectrin I are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin II (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Activation of calpain results in the breakdown of spectrin II, a neuronal cytoskeleton protein.

UniProt: Q13813

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization