P-Cadherin anticorps (AA 236-645)
Aperçu rapide pour P-Cadherin anticorps (AA 236-645) (ABIN7872634)
Antigène
Voir toutes P-Cadherin (CDH3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 236-645
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Fonction
- P-Cadherin Antibody / CDH3
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Purification
- Antigen affinity purified
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Immunogène
- Recombinant human protein (amino acids Q236-E645) was used as the immunogen for the P Cadherin antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the P Cadherin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the P Cadherin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- P-Cadherin (CDH3)
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Autre désignation
- P-Cadherin
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Sujet
- Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
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UniProt
- P22223
Antigène
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