STS anticorps (AA 24-193)

N° du produit ABIN7872671

Cet anticorps Lapin Polyclonal détecte spécifiquement STS dans WB, ELISA, FACS et IF. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour STS anticorps (AA 24-193) (ABIN7872671)

Antigène: STS (Steroid Sulfatase (STS))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STS est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-STS anticorps

Épitope: AA 24-193

Fonction: Asc Antibody / Pycard / Tms1

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant mouse protein (amino acids K24-S193) was used as the immunogen for the Asc antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Asc antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Asc antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur STS

Antigène: STS (Steroid Sulfatase (STS))

Autre désignation: Asc

Sujet: PYCARD, often referred to as ASC (Apoptosis-associated speck-like protein containing a CARD), is a protein that in humans is encoded by the PYCARD gene. This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9EPB4

Pathways: Steroid Hormone Biosynthesis, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation