DCT anticorps (AA 24-519)
Aperçu rapide pour DCT anticorps (AA 24-519) (ABIN7872702)
Antigène
Voir toutes DCT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 24-519
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Fonction
- DCT Antibody / L-dopachrome tautomerase / TYRP2 / TRP2
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Purification
- Antigen affinity purified
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Immunogène
- Recombinant human protein (amino acids Q24-A519) was used as the immunogen for the DCT antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the DCT antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the DCT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- DCT (Dopachrome Tautomerase (DCT))
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Autre désignation
- DCT
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Sujet
- Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.
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UniProt
- P40126
Antigène
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