SFTPD anticorps (AA 241-336)

N° du produit ABIN7872740

Cet anticorps Souris Monoclonal détecte spécifiquement SFTPD dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SFTPD anticorps (AA 241-336) (ABIN7872740)

Antigène: SFTPD (Surfactant Protein D (SFTPD))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SFTPD est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SFTPD-4362

Détail du produit anti-SFTPD anticorps

Épitope: AA 241-336

Fonction: Pulmonary Surfactant-Associated Protein D Antibody

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein (within amino acids 241-336) from the human protein was used as the immunogen for the Pulmonary Surfactant-Associated Protein D antibody.

Isotype: IgG2b, lambda

Information d'application

Indications d'application: Optimal dilution of the Pulmonary Surfactant-Associated Protein D antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Pulmonary Surfactant-Associated Protein D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur SFTPD

Antigène: SFTPD (Surfactant Protein D (SFTPD))

Autre désignation: Pulmonary Surfactant-Associated Protein D

Sujet: Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated Collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials.

UniProt: P35247