Recombinant LI Cadherin anticorps (AA 242-418)
Aperçu rapide pour Recombinant LI Cadherin anticorps (AA 242-418) (ABIN7872758)
Antigène
Voir toutes LI Cadherin AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- AA 242-418
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Fonction
- Recombinant CDH17 Antibody / Cadherin 17 (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogène
- A recombinant fragment (within amino acids 242-418) of human Cadherin 17 protein was used as the immunogen for the recombinant CDH17 antibody.
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Isotype
- IgG2b, kappa
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Indications d'application
- Optimal dilution of the recombinant CDH17 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the recombinant CDH17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- LI Cadherin
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Autre désignation
- CDH17
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Sujet
- It recognizes a protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.
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UniProt
- Q12864
Antigène
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