Recombinant LI Cadherin anticorps (AA 242-418)

N° du produit ABIN7872767

Cet anticorps Souris Monoclonal détecte spécifiquement LI Cadherin dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant LI Cadherin anticorps (AA 242-418) (ABIN7872767)

Antigène: LI Cadherin

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LI Cadherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RCDH17-8514

Détail du produit anti-LI Cadherin anticorps

Épitope: AA 242-418

Fonction: LI Cadherin Antibody / Cadherin 17

Purification: Protein A affinity

Immunogène: A recombinant partial protein sequence (within amino acids 242-418) from the human protein was used as the immunogen for the LI Cadherin antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the LI Cadherin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the LI Cadherin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur LI Cadherin

Antigène: LI Cadherin

Sujet: It recognizes a protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.

UniProt: Q12864