Recombinant LI Cadherin anticorps (AA 242-418)

N° du produit ABIN7872769

Cet anticorps anti-LI Cadherin Monoclonal Souris (Clone rCDH17-8512) (ABIN7872769) détecte spécifiquement LI Cadherin dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant LI Cadherin anticorps (AA 242-418) (ABIN7872769)

Antigène: LI Cadherin

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LI Cadherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RCDH17-8512

Détail du produit anti-LI Cadherin anticorps

Épitope: AA 242-418

Fonction: Cadherin 17 Antibody / CDH17

Purification: Protein A affinity

Immunogène: A recombinant partial protein sequence (within amino acids 242-418) from the human protein was used as the immunogen for the Cadherin 17 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Cadherin 17 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Cadherin 17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur LI Cadherin

Antigène: LI Cadherin

Autre désignation: Cadherin 17

Sujet: It recognizes a protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.

UniProt: Q12864