MMP13 anticorps (AA 249-471)

N° du produit ABIN7872824

Cet anticorps Lapin Polyclonal détecte spécifiquement MMP13 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MMP13 anticorps (AA 249-471) (ABIN7872824)

Antigène: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP13 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MMP13 anticorps

Épitope: AA 249-471

Fonction: Collagenase 3 Antibody / MMP13

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids K249-C471) was used as the immunogen for the Collagenase 3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Collagenase 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Collagenase 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MMP13

Antigène: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Autre désignation: Collagenase 3

Sujet: Collagenase 3 is an enzyme that in humans is encoded by the MMP13 gene. This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11.

UniProt: P45452