CDH6 anticorps (AA 250-450)

N° du produit ABIN7872908

Cet anticorps Souris Monoclonal détecte spécifiquement CDH6 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CDH6 anticorps (AA 250-450) (ABIN7872908)

Antigène: CDH6 (K-Cadherin (CDH6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDH6 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CDH6-3191

Détail du produit anti-CDH6 anticorps

Épitope: AA 250-450

Fonction: Cadherin 6 Antibody / CDH6 / K-Cadherin

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 250-450) from the human protein was used as the immunogen for the Cadherin 6 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Cadherin 6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Cadherin 6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CDH6

Antigène: CDH6 (K-Cadherin (CDH6))

Autre désignation: Cadherin 6

Sujet: This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. This protein may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.

UniProt: P55285

Pathways: Cell-Cell Junction Organization