Cyclin T1 anticorps (AA 253-281)

N° du produit ABIN7872934

Cet anticorps anti-Cyclin T1 Polyclonal Lapin (ABIN7872934) détecte spécifiquement Cyclin T1 dans WB et FACS. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Cyclin T1 anticorps (AA 253-281) (ABIN7872934)

Antigène: Cyclin T1 (CCNT1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin T1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-Cyclin T1 anticorps

Épitope: AA 253-281

Fonction: CCNT1 Antibody / Cyclin T1

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 253-281 from the human protein was used as the immunogen for the CCNT1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the CCNT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CCNT1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Cyclin T1

Antigène: Cyclin T1 (CCNT1)

Autre désignation: CCNT1

Sujet: CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.

UniProt: O60563