Tyrosinase-Related Protein 1 anticorps (AA 257-377)

N° du produit ABIN7872964

Cet anticorps anti-Tyrosinase-Related Protein 1 Monoclonal Souris (Clone TYRP1-3283) (ABIN7872964) détecte spécifiquement Tyrosinase-Related Protein 1 dans ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Tyrosinase-Related Protein 1 anticorps (AA 257-377) (ABIN7872964)

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Tyrosinase-Related Protein 1 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TYRP1-3283

Détail du produit anti-Tyrosinase-Related Protein 1 anticorps

Épitope: AA 257-377

Fonction: TRP1 / Tyrosinase-Related Protein-1 Antibody / TYRP1

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 257-377) was used as the immunogen for this TRP1 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the TRP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the TRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Tyrosinase-Related Protein 1

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Autre désignation: TRP1 / Tyrosinase-Related Protein-1

Sujet: It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

UniProt: P17643