GATA6 anticorps (AA 26-296)

N° du produit ABIN7872994

Cet anticorps anti-GATA6 Polyclonal Lapin (ABIN7872994) détecte spécifiquement GATA6 dans IHC (p). L’anticorps est réactif avec des échantillons de Poisson zèbre (Danio rerio).

Aperçu rapide pour GATA6 anticorps (AA 26-296) (ABIN7872994)

Antigène: GATA6 (GATA Binding Protein 6 (GATA6))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GATA6 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GATA6 anticorps

Épitope: AA 26-296

Fonction: Zebrafish Gata6 Antibody / GATA-binding factor 6

Purification: Antigen affinity chromatography

Immunogène: E. coli-derived zebrafish Gata6 recombinant protein (amino acids E26-E296) was used as the immunogen for the Zebrafish Gata6 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Gata6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Gata6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur GATA6

Antigène: GATA6 (GATA Binding Protein 6 (GATA6))

Autre désignation: Gata6

Sujet: GATA-binding protein 6 (Gata6) is a zinc finger transcription factor belonging to the GATA family, which regulates gene expression during embryonic development and cell lineage specification. In zebrafish (Danio rerio), Gata6 plays a key role in the development of the endoderm, heart, and gut, as well as in organ morphogenesis and tissue differentiation.

During early zebrafish embryogenesis, Gata6 is expressed in the endodermal and mesodermal layers, where it works in concert with Gata4 and Gata5 to specify endodermal fate and initiate the morphogenesis of organs such as the liver, pancreas, and intestine. It also contributes to cardiac progenitor specification and the formation of the heart tube, making it essential for proper cardiovascular development.

Due to its high conservation and central role in organogenesis, zebrafish Gata6 is widely used as a model to study developmental gene regulation, cardiogenesis, and congenital diseases affecting the heart and gastrointestinal tract. It is also a valuable marker for analyzing endodermal derivatives and early tissue patterning in vertebrate embryos.

UniProt: Q6NW63