L’anticorps anti-BUB1B Polyclonal Lapin est utilisé pour la détection de BUB1B dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF, IHC (p) et FACS.
BUB1B
Reactivité: Humain
IHC, ELISA, IF, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal dilution of the BubR1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
4 °C,-20 °C
Stockage commentaire
After reconstitution, the BubR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Antigène
BUB1B
(Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))
Autre désignation
BubR1
Sujet
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta is an enzyme that in humans is encoded by the BUB1B gene. This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.