RCC2 anticorps (AA 266-495)

N° du produit ABIN7873057

Cet anticorps anti-RCC2 Polyclonal Lapin (ABIN7873057) détecte spécifiquement RCC2 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Poisson zèbre (Danio rerio).

Aperçu rapide pour RCC2 anticorps (AA 266-495) (ABIN7873057)

Antigène: RCC2 (Regulator of Chromosome Condensation 2 (RCC2))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RCC2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RCC2 anticorps

Épitope: AA 266-495

Fonction: Zebrafish Rcc2 Antibody / Protein RCC2 homolog

Purification: Antigen affinity chromatography

Immunogène: E. coli-derived zebrafish Rcc2 recombinant protein (amino acids K266-L495) was used as the immunogen for the Zebrafish Rcc2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Rcc2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Rcc2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur RCC2

Antigène: RCC2 (Regulator of Chromosome Condensation 2 (RCC2))

Autre désignation: Rcc2

Sujet: Zebrafish Rcc2, known as regulator of chromosome condensation 2, is a multifunctional protein that plays a role in cell cycle progression, cytoskeletal dynamics, and cellular signaling. It is particularly involved in mitotic events, where it regulates processes related to chromosome condensation and segregation. Rcc2 is also known to interact with small GTP binding proteins such as Rac1, thereby influencing cell migration, adhesion, and actin cytoskeleton organization.

Zebrafish Rcc2 is an ortholog of the human RCC2 protein and shares significant sequence and functional similarity. In both species, Rcc2 functions as part of the chromosomal passenger complex and contributes to the accurate distribution of chromosomes during mitosis. Disruption of Rcc2 function can impair cell division and affect developmental processes, making it a key protein for studies of cell proliferation and morphogenesis.

Research on zebrafish Rcc2 is valuable for understanding its conserved roles in cell cycle regulation and cytoskeletal rearrangements. Zebrafish models allow for the exploration of Rcc2 function during embryogenesis, where rapid and precise cell division is essential for normal development.

Antibodies targeting zebrafish Rcc2 protein are important tools for studying mitosis, cytoskeletal organization, and related signaling pathways. The orthology between zebrafish Rcc2 and human RCC2 supports the use of zebrafish as a model to investigate fundamental mechanisms of cell division and to study pathways that may be altered in diseases such as cancer.

UniProt: Q6NYE2