ULBP1 anticorps (AA 27-209)

N° du produit ABIN7873093

Cet anticorps anti-ULBP1 Polyclonal Lapin (ABIN7873093) détecte spécifiquement ULBP1 dans ELISA, WB, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ULBP1 anticorps (AA 27-209) (ABIN7873093)

Antigène: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ULBP1 est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ULBP1 anticorps

Épitope: AA 27-209

Fonction: ULBP1 Antibody

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids W27-K209) was used as the immunogen for the ULBP1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the ULBP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the ULBP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ULBP1

Antigène: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Autre désignation: ULBP1

Sujet: UL16 binding protein 1 (ULBP1) is a cell surface glycoprotein encoded by ULBP1 gene located on the chromosome 6. The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9BZM6

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process